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The five most addictive substances on Earth and what they do to your brain

The most addictive drugs—which include crack cocaine, crystal meth, and prescription opioids—are also accompanied by intense withdrawal symptoms that make it difficult to quit. Drinking alcohol causes your brain to release dopamine and more endorphins. In addition to producing feelings of pleasure and satisfaction, these chemicals also act as natural painkillers. Different people’s brains react […]

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The promise of psychedelic medicine in psychiatry

In that study, nearly all of the compounds studied had greater potency in inducing AA release than in stimulating PI turnover. Some of these differences are noteworthy; for example, in psilocin, the potency for activating AA release was nearly 30-fold greater than for stimulating PI turnover. Buchborn et al. (2015) concluded that the differential receptor […]

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Effects of Performance-Enhancing Drugs

These symptoms — and the risk of fatal consequences — can be vastly reduced by seeking medical treatment at a specialized withdrawal and detox management facility. There are several medications that can directly lessen withdrawal symptoms, help you feel more comfortable, and allow you to withdraw safely. This is particularly true for college athletes, who […]

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DMT Side Effects and Risks to Know About

Beyond the sensory overload, DMT often brings about deep, spiritual, or psychological effects. Many users talk about feeling a profound connection to the universe, a sense of unity with everything around them. There are also stories of encounters with otherworldly entities or beings, which can range from friendly and guiding to intimidating or challenging. For […]

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